Hydrochlorothiazide can be given at doses of Apply a sun block product that has a skin protection factor SPF of at least The antihypertensive effects of the drug may be enhanced in the postsympathectomy patient. If you have a fever and there seems to be no reason for it, check with your doctor. Hydrochlorothiazide doses greater than 50 mg daily should be avoided. Increases in cholesterol and triglyceride levels may be associated with thiazide diuretic therapy. Make sure you tell your doctor if you have any other medical problems, especially: Also, use extra care during exercise or hot weather or if you must stand for long periods of time. Storage Keep out of the reach of children.
Periodic determination of hepatic function should be done particularly during the first 6 to 12 weeks of therapy or whenever an unexplained fever occurs. The usual daily dosage of methyldopa is mg to 2 g. Thus latent diabetes mellitus may become manifest during thiazide therapy. Make sure you tell your doctor if you have any other medical problems, especially: These in vitro studies were carried out both with and without exogenous metabolic activation. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. Several studies demonstrate a decrease in the bioavailability of methyldopa when it is ingested with ferrous sulfate or ferrous gluconate. If Aldoril does not adequately control blood pressure, additional doses of other agents may be given. Some patients may require a product with a higher SPF number, especially if they have a fair complexion. Pheochromocytoma—Methyldopa may interfere with tests for the condition. Vertigo, paresthesias, dizziness, headache, restlessness. It is very important to follow these directions. Marked hypercalcemia may be evidence of hidden hyperparathyroidism. Storage Keep container tightly closed. At four years of age, the developmental delay commonly seen in children born to hypertensive mothers was less evident in those whose mothers were treated with methyldopa during pregnancy than those whose mothers were untreated. Otherwise, management includes special attention to cardiac rate and output, blood volume, electrolyte balance, paralytic ileus, urinary function and cerebral activity. However, it is best to plan your dose or doses according to a schedule that will least affect your personal activities and sleep. Remember that this medicine will not cure your high blood pressure but it does help control it. Methyldopa should not be continued if edema progresses or signs of heart failure appear. Since both components of ALDORIL have a relatively short duration of action, withdrawal is followed by return of hypertension usually within 48 hours. These hepatic changes may represent hypersensitivity reactions. This is more likely to happen when you begin to take it or when you increase the amount of medicine you are taking. This is more important if you are already on a special diet as for diabetes , or if you are taking a potassium supplement or a medicine to reduce potassium loss. If a positive Coombs test develops during methyldopa therapy, the physician should determine whether hemolytic anemia exists and whether the positive Coombs test may be a problem. If the indirect Coombs test is also positive, problems may arise in the major cross match and the assistance of a hematologist or transfusion expert will be needed.
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